At low doses, retinal can be gentle enough on a compromised or sensitive skin that it doesn’t cause the same level of irritation, yet strong enough to stimulate cell renewal, ultimately leading to a more youthful, more even toned and textured complexion. Osmosis have nailed this formulation in Osmosis Skincare Calm Gentle Retinal Serum which combines powerful Retinal with calming and nourishing ingredients that help your skin to heal, rather than harm.